China Leading Company
Based in Silicon Valley
About Our Client
A leading IVDIVD solutions provider.
- Develop complex primary immune cell based assays, execute high-throughput screens using a variety of readout technologies, and evaluate hits for therapeutic potential;
- Working collaboratively with project team leaders to obtain a working knowledge of various therapeutic targets and participate in structural decisions to facilitate therapeutic antibody generation;
- OptimizeOptimize therapeutic antibodies through humanizationhumanization, affinity maturation and manufacturabilitymanufacturability engineering;
- Contribute to development of new screening technologies and discovery platforms as a member of a multidisciplinary team;
- Perform laboratory bench work and present scientific findings and project updates to line and/ or senior management;
- Collaborate with biology colleagues to generate appropriate in vitrovitro / cellular / in vivovivo data packages supporting PoCPoC;
- Engineering antibodies to maximizemaximize their therapeutic potential.
The Successful Applicant
- PhPh.D. in immunology, cancer immunology ,cell biology, molecular biology with 0-5 years of post-doctoral research experience;
- Significant expertise with in vitrovitro cell based assays utilizingutilizing primary cells is required; experience with myeloidmyeloid cell populations such as monocytesmonocytes, dendriticdendritic cells, or macrophagesmacrophages is preferred;
- Deep understanding of antibody structure and function;
- Significant research experience as demonstrated by track record of publications and scientific accomplishments Hands-on experience with in vitrovitro antibody discovery display technologies (e.g., phage, yeast display);
- Work in a collaborative environment with functional and therapeutic areas Adapt to rapid changes in project priorities and timelinestimelines;
- Antibody/antibody fragment library design and construction;
- Experience in antibody engineering and optimizationoptimization (e.g., humanizationhumanization, FcFc optimizationoptimization).
What's on Offer
- CozyCozy and profitable company
- High potential development career